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- you are allergic to any ingredient in Nitrofurantoin
- you are pregnant and at term (38 to 42 weeks pregnant), you are about to go into labor, or you are in labor
- you have decreased kidney function, decreased urination, or you are unable to urinate
- you have a history of liver problems or yellowing of the skin or eyes after taking any form of Nitrofurantoin
- the patient is younger than 1 month old.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Nitrofurantoin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have anemia, diabetes, electrolyte problems, glucose-6-phosphate dehydrogenase (G6PD) deficiency, kidney problems, liver problems, nerve problems (eg, peripheral neuropathy), porphyria (a certain blood problem), or low levels of vitamin B in your blood
- if you have a history of lung problems (eg, diffuse interstitial pneumonitis, pulmonary fibrosis)
- if you have very poor health.
Some medicines may interact with Nitrofurantoin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Probenecid or sulfinpyrazone because they may increase the risk of Nitrofurantoin’s side effects or decrease Nitrofurantoin’s effectiveness.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Nitrofurantoin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
- Nitrofurantoin may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Nitrofurantoin with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
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- Use Nitrofurantoin with caution in the elderly; they may be more sensitive to its effects, especially lung or liver problems.
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- Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nitrofurantoin while you are pregnant. Do NOT take Nitrofurantoin if you are at term (38 to 42 weeks pregnant), if you are about to go into labor, or if you are in labor. Nitrofurantoin is found in breast milk. Do not breast-feed infants younger 1 month while you are taking Nitrofurantoin. If your child is older than 1 month, check with your doctor. Discuss any possible risks to your baby.
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All medicines may cause side effects, but many people have no, or minor, side effects.
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Gas; headache; loss of appetite; mild diarrhea; nausea.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody or watery stools; bluish skin or nails; blurred vision or other vision changes; butterfly-shaped rash on the nose and cheeks; confusion; joint or muscle pain; mood or mental changes (eg, depression); persistent feeling of being unwell; persistent headache; red, swollen, blistered, or peeling skin; severe or persistent diarrhea; severe stomach pain or cramps; symptoms of liver problems (eg, yellowing of the eyes or skin, pale stools, severe or persistent nausea or loss of appetite, stomach pain); symptoms of lung problems (eg, fever, chills, chest pain, shortness of breath, unusual or persistent cough); tingling, numbness, or burning of the hands or feet; unusual bruising or bleeding; unusual tiredness or weakness.
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